Postdoctoral Fellow - CAR T/NK Cells and Oncolytic Virus - Yu Laboratory

City of Hope

Duarte, CA

Job posting number: #7085315 (Ref:10006142-9)

Posted: September 15, 2021

Application Deadline: Open Until Filled

Job Description

Thank you for your interest. Please note, the purpose of this posting is to recruit for on-going and future positions.

About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary

The City of Hope National Medical Center is looking for several highly motivated and creative Postdoctoral Fellows to work in either of the following four areas within the laboratories of Dr. Michael A. Caligiuri, President of City of Hope, and Dr. Jianhua Yu, a Professor in the Department of Hematology & Hematopoietic Cell Transplantation and the Department of Immuno-Oncology, Comprehensive Cancer Center: 1) novel oncolytic virus (e.g., herpes virus-based) engineering and its interaction with host immune cells; 2) antibody generation by phage display and/or animal immunization and bispecific antibodies; 3) chimeric antigen receptor (CAR) T or CAR natural killer (NK) cells; 4) NK cell biology including NK cell development and cell signaling. The group conducts the most forefront science and is highly productive with publications in high-impact journals such as Nature Biotechnology , Nature Immunology , Immunity , Cancer Discovery , JCI , etc. in the past two years. City of Hope is located in the pleasant city of Los Angeles of Southern California.

Key Responsibilities include:
  • Devise, plan, document and advance basic science and translational projects in the relevant research area
  • Collect data for grant applications and prepare manuscripts for publication
  • Work in close collaboration with other team members and external partners from academia and industry, including presentation of progress internally or externally
  • Train and supervise technical staff

Basic education, experience and skills required for consideration:
  • Recent PhD with a strong background and profound knowledge in the field of either virology, immunology, cancer immunology or immunotherapy
  • Previous experience in working with animal models of human cancers
  • Literature knowledge of one of the four research areas mentioned above
  • Evidence of scientific rigor and excellence as documented by high-impact peer-reviewed publications
  • Strong team player with excellent communication skills and fluency in English, both spoken and written
  • Commitment to the program at least for three years

Additional Information:
  • You will have the unique possibility to drive research towards a novel cancer therapy at the interface of science and translation to the clinic and publish high-impact journals. City of Hope offers a competitive salary of over $54,000 for a newly graduated PhD, which is higher than the NIH standard. The institution also offers medical insurance and other benefits.
  • Please send current CV/resume to or .

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.



  • Posting Date: Mar 23, 2020
  • Job Field: Research
  • Employee Status: Regular
  • Shift: Day Job

City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.

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