Postdoctoral Fellow - Super-Resolution Microscopy - NIH Funded

City of Hope

Duarte, CA

Job posting number: #7086481 (Ref:10012739-1)

Posted: October 4, 2021

Application Deadline: Open Until Filled

Job Description

Thank you for your interest. Please note, the purpose of this posting is to recruit for on-going and future positions.

About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary

A Postdoctoral Fellow Position is available in the laboratory of Dr. Tijana Jovanovic-Talisman . Biological nanoparticles that are continuously shed by cells - namely extracellular vesicles (EVs) - are an emerging and exciting strategy for performing minimally invasive diagnos es .

We seek a Postdoctoral Fellow with experience in cell biology and quantitative microscopy. Because EVs are loaded with disease specific molecules, they represent an excellent source of biomarker s . The project will develop and apply super-resolution microscopy methods to characterize EVs and their content. Specifically, super-resolution imaging will be used to characterize EVs from heart, brain, and immune cells. The approach will be also used to quantify a subpopulation of EVs associated with disease. Ultimately, the goal is to develop a new platform to perform molecular level diagnoses for precision medicine.

Key Responsibilities include:

The Postdoctoral Fellow will purify and manipulate EVs from cultured cells and plasma, perform imaging experiments using single molecule localization microscopy, and complete data analysis to characterize molecular content of extracellular vesicles.

Basic education, experience and skills required for consideration:
  • A Ph.D. degree in Biomedical Sciences, Biophysics, Chemical Engineering or a related discipline is required with no more than 4 years of postdoctoral training.
  • Experience in quantitative microscopy and cell biology.
  • Ability to carry out independent research and prepare manuscripts for publication.
  • Experience with super-resolution microscopy, extracellular vesicles, and MATLAB programing is preferred.


Additional Information:
  • To apply, please send your CV/resume to Dr. Talisman at ttalisman@coh.org .
  • To protect the health of patients and staff and to comply with new State of California mandates, City of Hope staff are required to show proof of full vaccination by September 30, 2021. Compliance is a condition of employment.


About Dr. Jovanovic-Talisman: Tijana Jovanovic-Talisman, PhD is an Associate Professor in the Department of Molecular Medicine . Dr. Talisman currently has multiple projects actively supported by the NIH. She and team are investigating biological processes that are critical to the progression of cancer and other diseases by using quantitative single molecule localization microscopy.

For more information on the Jovanovic-Talisman Lab, please click here .

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

#PD

  • Posting Date: Aug 4, 2021
  • Job Field: Research
  • Employee Status: Regular
  • Shift: Day Job


City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.


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