Postdoctoral Fellow - Treatment Development for Type 1 Diabetes (T1D)

City of Hope

Duarte, CA

Job posting number: #7092384 (Ref:10011060)

Posted: January 17, 2022

Application Deadline: Open Until Filled

Job Description

About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer, type 1 diabetes, type 2 diabetes and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

City of Hope has one of the most influential type 1 and type 2 diabetes research programs in the world. Our scientists’ work has revolutionized the understanding and treatment of the disease and continues today with exciting developments in cell transplantation, gene regulation, immune tolerance and gaining systemic understanding of diabetes as a complex, multifaceted disease.

To learn more about our exciting research and accomplishments in the field of Diabetes, please visit

Position Summary

We are seeking two Postdoctoral Fellows to support two key new projects. The first project will focus on protein engineering to create novel, disease activated bifunctional biologics.  The second project will have an emphasis on yeast display, library design, protein expression and characterization. 

These projects are part of a collaborative effort, funded by the Wanek T1D grant, between the laboratories of Dr. Bart Roep and Dr. John Williams to treat Type 1 Diabetes.   Experience in mammalian expression, protein purification, biophysical characterization (SPR, ITC, AUC and potentially X-ray and cryoEM), to cell based assays including but not limited to analytical cytometry and dissection of relevant signaling pathways is required.  The end goal is to advance clinical candidate that will impact patient’s life’s.

Basic education, experience and skills required for consideration:

  • PhD in chemistry, biochemistry, protein chemistry, biochemical engineering or related field with 1 to 3 years of postdoctoral experience
  • The ideal candidate will have a solid publication record 
  • Fully versed in protein purification methods
  • Excellent written and verbal communication skills
  • Good problem-solving skills

Additional Information:

  • For more information about Dr. Roep’s research, please click here.
  • For more information about Dr. Williams' research, please click here.
  • Please note, there are multiple Postdoctoral Training Fellowship positions available.

To protect the health of patients and staff and to comply with new State of California mandates, City of Hope staff are required to show proof of full vaccination by September 30, 2021.  Compliance is a condition of employment.   

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer.  All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.


City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.

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