Cell Manufacturing Associate Level II - CAR T Cell Therapies

City of Hope

Duarte, CA

Job posting number: #7100012 (Ref:10014602)

Posted: May 12, 2022

Application Deadline: Open Until Filled

Job Description

About City of Hope

City of Hope is an independent biomedical research and treatment organization for cancer, diabetes, and other life-threatening diseases.

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution.  AccessHope™, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hope’s specialized cancer expertise.

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

City of Hope’s commitment to Diversity, Equity, and Inclusion

We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all our communities.  Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds, and experiences to our work -- and that our teams align with the people we serve to build trust and understanding.  We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds, and perspectives; this is reflected in our work and represented in our people.

Position Summary

Cell Manufacturing Associate II position is available in the Cellular Therapy Production Center (CTPC).   This is a fast-paced lab involved in cutting edge technology, research and clinical immunotherapeutic programs.  New personnel will be trained in project specific techniques and procedures.

Key Responsibilities include:

  • Manufacture and test T cell products, under limited supervision, following established SOPs in cGMP facility.
  • Application of aseptic techniques.
  • Passage, maintain and cryopreserve cell cultures (e.g., T cell and tumor cell lines).
  • Provide routine lab support and maintenance activities.
  • Assist in developing and adapting new manufacturing procedures and analytical methodology.
  • Assist in creating, reviewing, and revising Standard Operating Procedures as necessary for cell product manufacturing and process development.
  • Meticulous attention to detail and accuracy in lab work and documentation, strictly following established SOPS, as well as accurate record keeping and lab documentation.
  • Cooperate with Quality Control (QC) and Quality Assurance (QA) groups to ensure the quality of product and cGMP compliance.
  • Assist in internal inspections and audits to ensure compliance with Federal Drug Administration (FDA) regulations and City of Hope and CTPC procedure requirements.
  • Required to wear pager, or other communication devices, to respond promptly to emergency calls and for critical equipment failure.
  • Complete and maintain all training required by City of Hope and CTPC.
  • Cooperate with other performance improvement and compliance activities within the department and in the institution.
  • Maintains current knowledge of manufacturing/analytical techniques and industry practices.

Basic education, experience and skills required for consideration:

  • Bachelor’s degree in biological science or related field, with at least 2 years of post-degree research experience.
  • 6 months or more of hands-on mammalian cell culture experience.
  • 6 months or more of cGMP experience.

Preferred education experience and skills:

  • Master’s degree in biological science or related field, with at least 1 year of post-degree research experience. 
  • Biotechnology or pharmaceutical industry experience.

Additional Information:

As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.

  • We have multiple positions available
  • To see more of the amazing work being done by our CAR T group please visit: https://www.cityofhope.org/research/car-t-cell-therapy

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer.  All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

#LI-CM



City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.


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Job posting number:#7100012 (Ref:10014602)
Application Deadline:Open Until Filled
Employer Location:City of Hope
Duarte,California
United States
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